The Psychosomatic Influence of Emotional Factors on the Prognosis of Psoriasis

Abstract

Psoriasis, a chronic autoimmune dermatosis, is influenced by emotional factors, especially stress, as highlighted by psychosomatic medicine. The disease, characterized by erythematous and scaly skin plaques, has a multifactorial etiology that includes genetic, immunological, and psychological factors. Stress can worsen psoriasis by intensifying the production of pro-inflammatory cytokines and exacerbating skin inflammation, creating a vicious cycle. Moreover, the psychological impact of psoriasis is significant, affecting patients’ self-esteem and quality of life, as they often face social stigmatization. Anxiety and depression are common among these individuals, underscoring the need for an interdisciplinary approach that integrates dermatological treatment and psychological support. Effective psoriasis management should address both physical symptoms and emotional factors, including the use of complementary therapies such as acupuncture and psychotherapy. The interaction between the hypothalamic-pituitary-adrenal axis and skin inflammation reinforces the importance of treating stress as part of psoriasis management. Interventions that promote emotional balance can improve therapeutic outcomes, highlighting the relevance of a holistic and multidisciplinary approach to disease management.