TRANSCRANIAL DIRECT CURRENT STIMULATION (tDCS) IN THE TREATMENT OFSCHIZOPHRENIA: EFFICACY AND PERSPECTIVES
DOI:
https://doi.org/10.51473/rcmos.v1i2.2024.650Keywords:
Schizophrenia. Transcranial direct current stimulation. tDCS. Cognition. Negative symptoms.Abstract
Schizophrenia is a severe mental disorder that affects millions of people worldwide,
characterized by psychotic symptoms, cognitive deficits, and behavioral alterations.
Transcranial direct current stimulation (tDCS) has emerged as a promising alternative for the
treatment of schizophrenia, particularly for negative symptoms and cognitive deficits that do
not respond satisfactorily to conventional treatments. This systematic review aimed to
investigate the efficacy and safety of tDCS in the management of schizophrenia by evaluating
recent studies and discussing future perspectives for the use of this technique. The analysis of
the included articles revealed that tDCS significantly improves cognitive function and
negative symptoms, as well as reduces the frequency and intensity of auditory hallucinations.
However, variability in treatment response and the need for standardization of stimulation
protocols remain important challenges to be addressed. The study concludes that tDCS has a
favorable safety profile and shows great potential as an adjunct in the treatment of
schizophrenia, especially when combined with other therapeutic interventions, such as
cognitive behavioral therapy.
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References
GUTTESEN, Liv Liebach et al. Repetitive transcranial magnetic stimulation and transcranial direct current
stimulation for auditory hallucinations in schizophrenia: systematic review and meta-analysis. Journal of
Psychiatric Research, v. 143, p. 163-175, 2021.
KUMAR, Pattath Narayanan Suresh et al. Transcranial direct current stimulation for refractory auditory
hallucinations in schizophrenia: Acute and 16-week outcomes. Indian Journal of Psychiatry, v. 62, n. 5, p.
-576, 2020.
PROSS, Benjamin et al. Anodal transcranial direct current stimulation sustainably increases EEG alpha activity
in patients with schizophrenia. Neuropsychopharmacology Reports, v. 42, n. 3, p. 323-332, 2022.
STRAUBE, Benjamin et al. Transcranial direct current stimulation improves action-outcome monitoring in
schizophrenia spectrum disorder. Brain Communications, v. 2, n. 2, p. fcaa151, 2020.
VALIENGO, Leandro da Costa Lane et al. Efficacy and safety of transcranial direct current stimulation for
treating negative symptoms in schizophrenia: a randomized clinical trial. JAMA Psychiatry, v. 77, n. 2, p.
-129, 2020.
YAMADA, Yuji et al. Transcranial direct current stimulation on the left superior temporal sulcus improves social
cognition in schizophrenia: an open-label study. Frontiers in Psychiatry, v. 13, p. 862814, 2022.
ZHOU, Yue et al. Efficacy and safety of Transcranial Direct Current Stimulation (tDCS) on cognitive function in
chronic schizophrenia with Tardive Dyskinesia (TD): a randomized, double-blind, sham-controlled, clinical trial.
BMC Psychiatry, v. 23, n. 1, p. 623, 2023.
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Copyright (c) 2024 João Vítor Mota Cachoeira, Ana Luiza Oliveira Nascimento Silva, Bruna Aguiar Valle, Lídia Di Bella Castro Rabelo (Autor/in)
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