CURRENT MANAGEMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE:THERAPEUTIC APPROACHES AND NEW PERSPECTIVES

Authors

  • Pedro Raydan Brandão Simões Author
  • Amanda Saori Fukushima Author
  • Davi Rezende Ribeiro Author
  • João Ricardo Buchemi de Carvalho Author

DOI:

https://doi.org/10.51473/rcmos.v1i1.2024.616

Keywords:

Bronchodilators. COPD. Inhaled Corticosteroids. Multidisciplinary Approach. Pulmonary Rehabilitation.

Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a highly prevalent chronic respiratory
condition characterized by progressive and irreversible airflow limitation. It is associated with
significant morbidity, with frequent exacerbations that increase hospitalization rates and
worsen patients' quality of life. This study reviews the latest therapeutic approaches in COPD
management, including pharmacological interventions such as long-acting bronchodilators,
inhaled corticosteroids, and biological agents, as well as non-pharmacological strategies such
as smoking cessation and pulmonary rehabilitation. Following an initial search of 6,973
studies, 32 articles were reviewed, leading to the inclusion of 9 key studies. The results
indicate that personalized treatment, combining medications and behavioral interventions,
improves lung function and reduces exacerbations. Interventions such as short-duration
antibiotic and systemic corticosteroid regimens proved effective in managing acute
exacerbations, while the use of non-invasive ventilation during the COVID-19 pandemic was
shown to be a viable alternative for COPD patients. It is concluded that COPD management
requires a multidisciplinary and personalized approach to optimize disease control and reduce
long-term complications.

Downloads

Download data is not yet available.

Author Biographies

  • Pedro Raydan Brandão Simões

    – Pontifícia Universidade Católica de Minas Gerais

  • Amanda Saori Fukushima

    – Pontifícia Universidade Católica de Minas Gerais

  • Davi Rezende Ribeiro

    – Pontifícia Universidade Católica de Minas Gerais

  • João Ricardo Buchemi de Carvalho

    – Pontifícia Universidade Católica de Minas Gerais

References

AL WACHAMI, N et al. Estimating the global prevalence of chronic obstructive pulmonary disease (COPD): a

systematic review and meta-analysis. BMC Public Health, v.24, p.297, 2024.

ARCHONTAKIS BARAKAKIS, P et al. High versus Medium Dose of Inhaled Corticosteroid in Chronic

Obstructive Lung Disease: A Systematic Review and Meta-Analysis. Int J Chron Obstruct Pulmon Dis, v.18,

p.469-482, 2023.

HAN, M et al. The effectiveness of theory-based smoking cessation interventions in patients with chronic

obstructive pulmonary disease: a meta-analysis. BMC Public Health, v.23, p.1510, 2023.

KARAGIANNIS, C et al. The effects of upper limb exercise training on upper limb muscle strength in people

with chronic obstructive pulmonary disease: a systematic review and meta-analysis of randomized controlled

trials. Ther Adv Respir Dis, v.17, p.17534666231170813, 2023.

MESSOUS, S et al. Two-day versus seven-day course of levofloxacin in acute COPD exacerbation: a

randomized controlled trial. Ther Adv Respir Dis, v.16, p.17534666221099729, 2022.

PAPI, A et al. N-acetylcysteine Treatment in Chronic Obstructive Pulmonary Disease (COPD) and Chronic

Bronchitis/Pre-COPD: Distinct Meta-analyses. Arch Bronconeumol, v.60, p.269-278, 2024.

SINGH, D. Pharmacological treatment of stable chronic obstructive pulmonary disease. Respirology, v.26,

p.643-651, 2021.

WU, TT et al. Real-World COPD Management Over 3 Years at the Community Health Service Center of

Shanghai During the COVID-19 Pandemic in China. Int J Chron Obstruct Pulmon Dis, v.18, p.349-364, 2023.

ZHAO, Z et al. Long- versus short-duration systemic corticosteroid regimens for acute exacerbations of COPD:

A systematic review and meta-analysis. PLoS One, v.18, p.e0296470, 2023.

Published

2024-09-20

How to Cite

SIMÕES, Pedro Raydan Brandão; FUKUSHIMA, Amanda Saori; RIBEIRO, Davi Rezende; DE CARVALHO, João Ricardo Buchemi. CURRENT MANAGEMENT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE:THERAPEUTIC APPROACHES AND NEW PERSPECTIVES. Multidisciplinary Scientific Journal The Knowledge, Brasil, v. 1, n. 1, 2024. DOI: 10.51473/rcmos.v1i1.2024.616. Disponível em: https://submissoesrevistacientificaosaber.com/index.php/rcmos/article/view/616.. Acesso em: 13 nov. 2024.

Similar Articles

11-20 of 125

You may also start an advanced similarity search for this article.